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Especially higher perchlorate concentrations led to conspicuous alterations in thyroidal tissue architecture and to effects in the pituitary.
A reduction in desmosome formation during EMT correlates with conspicuous alterations in intermediate filaments; cytokeratins, almost disappear from within the cell, while the mesenchymal-type intermediate filament protein, vimentin, is up-regulated [2], [6] [8].
This finding suggests that the dysfunction of the heart observed in diabetes may be caused by conspicuous alterations of myocardial metabolism caused by insulin deficiency, which can be reversed by means of exogenous replacement of the hormone.
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The most conspicuous alteration was extensive myelin degradation, with the formation of myelin ovoids and the presence of phagocytic cells engulfing large amounts of lamellar myelin debris and 3(b)).
Conspicuous ultrastructural alterations seen in articular chondrocytes (vacuolated cytoplasm and loss of nuclei) and synoviocytes (disintegrating nuclei and vacuoles, synovial adhesions) of untreated or scrambled-P-NT.II-treated Tg197 mice were absent in the P-NT.II-treated Tg197 group.
Fibrosis is the most conspicuous pathological alteration in dystrophic muscle.
The alteration is conspicuous in Phalaenopsis and Agrostis, whose loops are even longer (41 and 47 bp, respectively) than most of others (37 bp) due to the variation near the two ends of the loop in the stem region (Figure 5).
Parent-of-origin has a conspicuous effect on the alteration frequencies.
Other damages that were less conspicuous include: erosion of the centriole, alterations in the parenchyma and general architecture of the liver, as well as infiltration of the liver by immune cells.
In concordance, the results presented in this paper demonstrate that CD and LA provoked severe morphological alterations, among them, the most conspicuous were the shrank caudal region; therefore it suggests that actin participate in the caudal movement.
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