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Capped dredged material was placed in a consolidation cell and pore water expelled during the consolidation was collected for chemical analysis.
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The authors reported that flagellar genes were highly up-regulated in both swarming and consolidation cells compared to cells cultured in broth.
Specifically, it influences the dendritic spine density, synapse maturation, memory consolidation and cell survival, and it may be involved in certain neuropathologies (Henson et al., 2010; Low and Wee, 2010).
Again, it was found that much more severe necrotizing bronchitis, large areas of pulmonary consolidation with inflammatory cell infiltrates and moderate-to-severe pulmonary edema were found and were more frequently observed in infected pregnant mice (Fig. 5Ad) than in non-pregnant mice (Fig. 5Ac) infected by mutant virus.
After consolidation, allogeneic stem cell transplantation (alloSCT) is an option for selected patients.
By contrast, non-inferiority was demonstrated for empirical versus pre-emptive treatment in a subgroup of patients who received consolidation therapy/autologous stem cell transplantation.
The rate of IFDs was significantly higher in a subgroup of patients who received induction therapy (16.4 %) versus patients who received consolidation therapy/autologous stem cell transplantation (3.9 %, p < 0.01), with 15/17 IFD cases occurring in the induction group and most infections occurring in the pre-emptive arm (12 cases of IFD).
This choice is also apparent during blood vessel consolidation, as endothelial cells via Dll4 and PDGF-BB promote the pericyte fate even in committed myoblasts [ 33].
The distinct waves of swarm fronts (Fig. 3) are somewhat similar in appearance to the concentric rings produced by Proteus spp., which represent phases of consolidation, where swarm cells repeatedly de-differentiate and re-differentiate in spatially defined cycles (12).
First-line treatment for most PTCLs should include multi-agent chemotherapy with consideration of inclusion of etoposide chemotherapy for younger patients, as well as consolidation with autologous stem cell transplantation (SCT) in select cases.
Chemoimmunotherapy (combination with rituximab) is the routine first-line therapy, although data strongly suggest a benefit from intensification through high-dose therapy with stem cell transplantation consolidation or doseintense chemotherapy with HyperCVAD (fractionated cyclophosphamide/vincristine/doxorubicin/dexamethasone)/rituximab.
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