Sentence examples for consolidating pathways from inspiring English sources

A de novo method for consolidating pathways independent of specific experiments that still handles the problems of set matching and numerical identification of subset similarity allows empirical comparison and consistent results.

While this might seem to offer a way to significantly consolidate pathways, there exist overlapping pathway gene sets that make consolidation difficult.

Here, we have outlined possible bioinformatics workflows to consolidate pathway information in one species (P. trichocarpa) based on experimentally derived knowledge available for other plant species (A. thaliana).

We propose three different methods to consolidate multiple pathways into one pathway concept.

Pathways that do not consolidate into pathway concepts are not contained in their own division and do not share similar symbols.

To consolidate further, pathways that are similar could be combined when they have sufficiently similar gene sets, however the difficulty is determination of "sufficiently similar".

After gene set enrichment finds representative pathways for large gene sets, pathways are consolidated into representative pathway concepts.

One is tightly associated with the results from gene expression experiments consolidating only enriched pathways.

To address this, we exercised a combination of hierarchical clustering and nearest neighbor graph representation, with judiciously selected cutoff values, thereby consolidating 3215 human pathways from 12 sources into a set of 1073 SuperPaths.

Like the previous example, all three pathways could be consolidated into one "pathway concept" simply by observing the identical gene membership in sets.

In an effort to describe and consolidate knowledge of pathways central to macrophage activation we have constructed a pathway diagram based on published literature.