A decade seems a good stretch in which to make a mark; not too long to get jaded, yet substantial enough to develop and consolidate ideas.
So in November 2014, the Neurodata without Borders initiative which is supported by the Kavli Foundation, GE, Janelia Farm, Allen Institute for Brain Science and the International Neuroinformatics Coordinating Facility (INCF hosted a hackathon to consolidate ideas for designing and implementing a standard neuroscience file format.
That explains why South Korea has just named its first chief technology officer, Chang-Gyu Hwang, the former CTO of Samsung, who told me his goal is to consolidate ideas and invest in long-term research that companies cannot afford.
The process of developing the logic model provided an opportunity for the team to share and consolidate ideas and emerged as a convenient communication tool.
"Chris very casually mentions ideas: 'Wouldn't it be nice to figure out a way of consolidating the ideas of relativity, time and quantum mechanics?' So I go off — I don't actually have to do it; I just have to make you feel as if it's happening," he says, laughing.
Sometimes I'll start a session by displaying the challenge question ("In what ways might we do X differently?") on an easel pad, and kick off the brainstorm by having participants jot down their ideas on individual sticky notes for a period of quiet time before coming together as a team to consolidate the ideas (eliminating duplicate ideas).
Performances are quite similar, consolidating the idea that, waste heat from cogeneration can be re-used with 78% of efficiency.
Taken together, these interactions of embelin and TACE were expected to interfere with the interaction of substrate to the active site of TACE, hence consolidating the idea of embelin as TACE inhibitor.
Biochemical, electrophysiological, and in vivo imaging studies are consolidating the idea that occupancy of different receptors generates a nonuniform pattern of activation of cAMP effector proteins such as PKA (cAMP-dependent protein kinase).
In its six months Ami has investigated many technologies and ideas; an obvious follow-on to the project is to consolidate these ideas into a fully integrated tool that can be used in real laboratories.
