Exact(3)
We consolidated interactions from mouse and rat into human by converting all protein/gene IDs to human Entrez gene symbols.
Secondly, iRefWeb allows the retrieval of consolidated interactions that match various user-defined criteria, such as the number of supporting publications or low- versus high-throughput studies.
To produce consolidated interactions from a single cluster, each of its members (interactions) is identified with its PSI-MI term for information-detection method.
Similar(55)
iRefWeb allows filtering interactions by specifying a threshold (say, three or more) for the 'Number of Interacting Proteins' in the consolidated interaction record.
The three processing steps are: (i) mapping all interactants to NCBI Gene IDs and removing all undesired raw interactions; (ii) deflating potentially expanded complexes; and (iii) collecting all raw interactions, originated from a single publication, that have the same interactants and compatible experimental detection method annotations into one consolidated interaction.
The goal of the final phase of ppiTrim is to consolidate all evidence for an interaction, obtained from a single experiment, into one consolidated interaction record.
The proposed architecture illustrates the consolidated interaction between intelligent agents and distributed CBR-PDSs in a PTI framework.
S.R. consolidated interaction data using the iRefIndex procedure.
Ideally, one would want to have a reliability score associated with each consolidated interaction.
Interactions from each subcluster are collected into a single consolidated interaction, which is output to the final data set.
For easier reference, each consolidated interaction is given a unique ppiTrim ID, which is similar to RIGID from iRefIndex.
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