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The ability to produce consistently fatal disease in a host is often of negative survival value to the parasite, because it is quite likely to eliminate quickly all available hosts.
In Tasmania there is emerging evidence that feral cat populations are increasing following wide-ranging and extensive declines in the apex predator, the Tasmanian devil, from a consistently fatal transmissible cancer.
Although serious, diphtheritic polyneuropathy is not consistently fatal and may resolve.
In 1929, the conventional notion that coccidioidal infections were rare and consistently fatal was questioned after Harold Chope, a medical student, accidentally inhaled Coccidioides spores from a culture plate in the Stanford University laboratory of Ernest Dickson.
Death certificate data is deemed a reliable way of estimating disease incidence only in conditions which are well defined, rarely misdiagnosed, and consistently fatal without changing survival (Marin et al, 2011).
Many of the dramatic developments in the earlier history of the HIV epidemic were driven by a focus on HIV's acuity rather than its chronicity--its initially slow but consistently fatal progression, its remarkable ability to evade anti-retroviral treatments and vaccines, the significant stigma attached to it, and the scale of the epidemic.
Similar(53)
To date, however, there are only 3 viruses, two clade A and one clade C, which have been shown to consistently cause fatal immunodeficiency disease in cats under experimental conditions and only one of these 3 has been molecularly cloned [38], [40], [41].
Even if intoxication with the emetic toxin cereulide in most cases produces only mild symptoms, consistently also fatal cases are reported [ 6– 8].
While significant alterations were observed in all cytokines during the monitoring period, IL-6 levels remained consistently higher in fatal cases and TNF-α levels increased in both in fatal and non-fatal CCHF cases.
In a large prospective community-based cohort, depressive symptoms at baseline were consistently associated with fatal coronary heart disease and stroke events [46].
The episode linked traffic-stop violence during Jim Crow to the present day, years before mainstream media began consistently covering the epidemic of fatal police traffic stops for African Americans.
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CEO of Professional Science Editing for Scientists @ prosciediting.com