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Conditional essentiality has not been explicitly addressed in this study since the main focus was to identify those that are consistently essential in the WT condition.
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Given that several key genes decisively affect a specific cancer, we posit that the proposed model consistently selects essential factors, in contrast to a random selection.
Consistently, the essential oil represses signaling pathways and cell cycle regulators that have been proposed as therapeutic targets for breast cancer.
Because CIUE is not defined consistently, it is essential to clearly define this condition.
Most of the signaling proteins and interactions in the network have been consistently identified as essential markers of the response or resistance to the selected targeted drugs in multiple cell lines, in vivo mouse models, and patient tumors.
If you are not acting consistently with your essential self, how can you expect to create and authentic relationship?
Consistently, Hsp60 is essential to maintain apoptosis inhibition preserved by Lon overexpression.
Consistently, with its essential role in motivated behaviors, several genes within the dopamine system were altered by central ghrelin treatment.
Research has found that people who consistently use sesquiterpenes essential oil have a higher level of resistance to illness than the average person [ 32].
As a group, public health workers consistently rated two essential public health themes among the top training needs: enforcing laws and regulations to protect health; and informing, educating, and empowering people about health issues.
Past extensive studies have consistently demonstrated the essential role of TGF- β and its downstream Smad signaling had in the pathogenesis of renal fibrosis, but the causative factors that trigger TGF- β expression and the molecular mechanisms that initiate the above-described cellular events are yet to be fully addressed.
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