Exact(1)
We provide an efficient algorithm for estimation of model parameters, and show that the proposed method can consistently discover causal relationships in the large p, small n setting.
Similar(58)
Furthermore, the effect has been highly replicable: we ourselves have consistently discovered such effects in more than a dozen experiments, and our gaydar research was inspired by the work of the social psychologist Nicholas Rule, who has published on the gaydar phenomenon numerous times in the past few years.
For likely over a decade, Atlanta has been considered a hip-hop mecca -- consistently discovering new hip-hop artists and featuring them on V-103, Hot 107.9 or Street 94.5.
Only SNPs that were consistently discovered in parents and the progenies were retained [ 50].
The principle assumption of our study is that the pathways that relevant to the disease mechanism should be consistently discovered in a number of independent studies.
Four (22%) PN-DMR genes, 9 (60%) NN-DMR genes and 2 (33%) NEC-DMR genes were consistently discovered with DMRs in the validation results, which all agreed with RRBS results (Additional file 1: Table S6).
We used MACS2 (-B –broad –g 740000000 trackline) (Zhang et al. 2008) and SICER (window size 200 bp, gap size 400 bp, effective genome fraction 0.4, redundancy threshold 1, fragment size 150 bp, and FDR 0.05) to identify histone modification peaks in centromeres, and retained peaks that were consistently discovered by both algorithms for further analysis.
Consistently, we discovered significantly decreased protein levels of full-length TrkB (TrkB-FL), a trend towards increased truncated TrkB isoform protein levels and significantly altered TrkB isoform ratios in autism versus control subjects, supporting a TrkB isoform imbalance in autism similar to other neuropsychiatric disorders such as schizophrenia [ 52, 53].
This is a label that enables large databases to be searched quickly and consistently, and to discover new insights into chemistry.
Human beings, although they have invented air-conditioning, cured polio and hit.400 in a regulation Major League season, have consistently failed to discover the secret to managing a fractional-reserve banking system.
The voters, they discovered, consistently reserved their highest marks for moments when Mr. Romney sounded bipartisan and moderate, two themes he has long played down on the campaign trail but seemed to take pains to showcase this week with centrist-sounding statements on taxes, abortion and immigration.
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