None of these probes are consistently deleted in any of the other samples studied.
A large set of genes were consistently deleted in the three clinical isolates.
Consistently, deleting both of the Ig1 and Ig2 domains from Robo2 results in a diminished interaction with Robo1 in vivo and in vitro.
Given that the second BRCA2 allele is consistently deleted from cancer cells [37, 38], we used gene targeting to introduce the corresponding P3240L mutation into one allele of GgBrca2, while deleting the second allele, to recapitulate cancer-associated genetic alterations.
EI24 is a p53-induced DNA damage response gene involved in growth suppression and apoptosis, located on a region in the human genome most consistently deleted in solid tumors (11q23) (Gu et al., 2000).
We identified single base differences throughout the genome between the diploid genomes and discovered that 978 genes of the D-genome reference sequence are consistently deleted in the A-genome.
Consistently, deleting the bulge results in exclusively monomeric binding, and previous studies showed that simply introducing bulges with variable sequences juxtaposed to IIB is sufficient to mediate co-operative Rev binding (Zemmel et al., 1996).
Horrigan et al. identified a 1 1.5 megabase region at chromosome 5q31 that was consistently deleted in a cohort of patients with del 5q) MDS or AML (not including patients with "5q– syndrome"—a subclass of disease characterized by <5 % BM blasts and specific morphology and blood counts) [ 12].
The alteration patterns of the FHIT gene expression in high-grade CINs were virtually similar to those found in invasive carcinomas, such that the exons 5 7 were consistently deleted associated or unassociated with loss of the exon 4 and/or 8.
In one CQI development project surgeons argued that the word "quality of care" should consistently be deleted in the research report, because patient experiences -in their opinion- measure something completely different than quality of care.
