In terms of functional outcomes, both the ROM recovery and the LES scoring system improved during the study in both groups from presurgery to last follow-up visit, consistent with the clinical relevance and validity of our arthroscopic surgical procedure and the results of recent findings [4, 25, 26].
Consistent with the biological relevance of these findings, ATM promoted tumor formation in a xenograft human breast cancer cell model.
Furthermore, double mutant mice showed a remarkable recovery of skin and immunological alterations, which is consistent with the proposed relevance of NF-κB activity in tissue homeostasis maintenance.
Therefore, our results further suggest that PRL-3 per se can be another novel causal factor for AML progression, as PRL-3 silencing can succeed against the AML pathogenesis in vivo, which is consistent with the clinical relevance of PRL-3 to AML prognosis (Fig. 6 and Table 3).
Consistent with the reported clinical relevance of this model [ 23], here principal component analysis based on the expression of these novel genes identified by LongSAGE, clustered the clinical samples of CRPC separately from the androgen-dependent samples.
TGF- β2-targeted therapies are currently evaluated in randomised clinical trials (Fakhrai et al., 2006; Schlingensiepen et al, 2006) in consistent with the reports on the relevance of TGF- β2 for the progression of high-grade gliomas.
Thus, the observed 31.5 % reduction in the rate of positive blood cultures in patients with prior Lyme disease in that study is consistent with the existence and clinical relevance of type specific immunity.
Since BMP4 is known to increase osteoblast differentiation the affection of the skeletal system would be consistent with a functional relevance of the newly identified c.899G > C substitution.
Statistical analyses further confirmed that this enrichment of YY1 binding motifs is consistent with functional relevance and has likely been driven by unknown selection pressure at the DNA level.
In contrast, consistent with their relevance in endometrial receptivity [12], CD15, L-selectin ligands, were detected on the cell surface of both primary EEC and in a small percentage of cells from the receptive RL95-2 line, but not on HEC-1-A cells.
