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This observation was consistent with the progression of bacterial burdens in human ear infections in the absence of antibiotics [20].
All in all, these data are consistent with the possibility that lupus autoimmunity as detected by autoantibody binding is initiated by a single autoantibody specificity, which is also consistent with the progression of epitope spreading in lupus described previously [16] [22] and, also, hereby becomes a hypothesis to be further tested by future experiments.
This observation is consistent with the progression of Toxoplasma gondii, another Apicomplexan parasite, through its tachyzoite cell cycle [ 12].
This cell line has a higher EGFR/VRK2 ratio and lower levels cyclin D1 consistent with the progression of cell cycle after serum readdition.
Moreover, the relaxin concentration in CSF was elevated after SAH, and the time course of elevation of relaxin in CSF was consistent with the progression of cerebral vasospasm.
The overall temporal sequence - optix expression followed by cuticle gene expression, which in turn was followed by pigment gene expression - is consistent with the progression of wing development, as scale maturation and sclerotization precedes the appearance of pigments.
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This is consistent with the clinical progression of the PSACH phenotype in which patients are normal at birth but during childhood they exhibit progressive short-limbed dwarfism [ Maroteaux and Lamy, 1959; Rimoin et al., 1994].
Since IL-10 is a powerful anti-inflammatory cytokine and its genetic ablation in mice promotes atherosclerotic lesion formation (Mallat et al, 1999), these results suggest that Rcan1 deficiency promotes the presence of macrophages with anti-inflammatory properties in the atheroma plaque, a conclusion consistent with the retarded progression of lesions in Apoe −/− Rcan1 −/− mice.
This is consistent with observations that triacylglycerol levels correlate with the progression of diabetic neuropathy [ 92], with clinical trials [ 93], cohort studies [ 94, 95] showing benefits of statin treatment in type 2 diabetes, and with animal studies showing restoration of vasa nervorum function and reversal of diabetic neuropathy after statin treatment [ 96].
It showed that homocysteine gradually increased with the progression of AD, which was consistent with previous findings [ 29].
With the progression of the disease, contractile parameters showed consistent deterioration.
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