The DEHD substrate (designed for Caspase-2) produced results very similar to DEVD, showing activation by Caspases-2, -3, and -7, consistent with prior substrate specificity experiments suggesting that the P2 position where H was placed is the most flexible residue for Caspases-3 and -7 substrates [20].
These findings, which are the first to document an interaction of TG2 with histone proteins in an intact cell, are consistent with prior test tube experiments that have shown that TG2 can post translationally modify histone proteins (Ballestar et al, 1996, 2001; Ballestar & Franco, 1997).
If the hypothesized core pathway is validated by experiments, or consistent with prior knowledge, the association with the core pathway can prioritize the driver mutation.
Rapid first pass metabolism (<2 hr) consistent with prior reports confounded the interpretation of systemic delivery experiments (Callaway et al., 1999).
The finding that participants perceived the vertical sizes of figures as larger in Experiment 1 but not in Experiment 2 in both the fixation and saccade conditions is consistent with prior research [19].
While future experiments are required to test this model directly, aspects of it are consistent with prior observations.
As that suggests, for a possible thing to seem plausible it must be reasonably consistent with our prior experience.
That finding was consistent with prior research.
That would be very consistent with prior Iraqi strategy".
Sample sizes were chosen to be consistent with prior work15,19,20.
The approach is therefore not consistent with prior law.
