The abnormalities in FMS patients are consistent with loss of HPA axis resiliency.
sec15− sensory organs contain extra neurons at the expense of support cells, a phenotype consistent with loss of Notch signaling.
The loss of FGF-1 is consistent with loss of differentiation in dysplasias and some squamous cell carcinomas.
After alkylation, the alkylated kerateines still formed hydrogels and the alkylation led to changes in the mechanical and visco-elastic properties of the materials consistent with loss of disulfide crosslinking.
With a decrease in soft segment chain length, the temperature of maximum shape recovery rate increased and the width of the recovery window decreased, consistent with loss of soft segment chain mobility remote from the crosslinks.
The negatively fractionated δ53Cr values measured in the weathering profile relative to the unaltered tonalitic bedrock characterized by a high temperature magmatic inventory Cr isotope signature are consistent with loss of a positively fractionated Cr VI) pool formed during weathering.
Reduction of the level of these factors is consistent with loss of renewal capacity.
The reduced b-wave amplitude is consistent with loss of amacrine cells (and cone bipolar cells).
In our trapping assay the same human deletion mutant showed reduced covalent complex formation, consistent with loss of enzymatic activity.
These observations are consistent with loss of the duplication due to unequal crossing-over, as discussed above.
Electron micrographs showed changes consistent with loss of a capsular structure [15] in the mutants that were selected.
