Sentence examples for consistent with impairment of from inspiring English sources
Importantly, rapamycin increased both LC3-II and Atg5-Atg12 conjugate levels, in both control cells and cells exposed to SIV-infected microglia supernatant (Figure 4A), consistent with impairment of autophagy.
These results are consistent with impairment of IKK function as this residue can be phosphorylated by IKK [ 22].
As previously demonstrated [ 12], TNF-α markedly reduced activity at this regulatory region consistent with impairment of Sox-9 binding or activity.
We noted significant loss of quadriceps muscle mass, consistent with impairment of limb function, which was more pronounced in infected limbs.
A recent cross-sectional study found that blood samples of oil spill workers showed alterations consistent with impairment of the hepatic and hematopoietic systems [ 20].
Furthermore, SPOP-wt increased RAD51 foci formation compared to controls, while SPOP-F133V-expressing cells showed a dramatic decrease in RAD51 foci formation, consistent with impairment of HDR.
The phenotype of the individual with the p.Val68Gly mutation closely mirrors patients with congenital myasthenic syndrome owing to DPAGT1 mutations, and our results are consistent with impairment, but not complete disruption of N-linked glycosylation.
Lentiviral-mediated knockdown of clathrin heavy chain substantially decreases the protein levels of clathrin heavy chain and evokes a twofold-increase in the levels of cell surface mLRP4 in N2a cells (Fig. 4A), consistent with an impairment of clathrin-mediated endocytosis of this LRP1 minireceptor.
Taken together, these findings demonstrate that Myc inhibition resulted in decreased clearance of different types of autophagy substrates, consistent with impairment in autophagy.
Here we found that, in diabetic LV, protein levels of both ATOX1 and ATP7B were decreased, consistent with possible impairment of copper supply for activation of cuproenzymes.
Therefore, taken together, these findings are consistent with an impairment of the insulinotropic effect of GLP1 after vagotomy, as also shown in rodents (10, 11, 55).
