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Consistent with alterations in mitochondrial content, autophagy-deficient T cells have increased reactive oxygen species production as well as an imbalance in pro- and antiapoptotic protein expression.
The mean FRC decreased by 36% in the SPA group, a decrease that is consistent with alterations in FRC characteristic of patients with ARDS [37].
Perturbations of the lamellar arrangement are consistent with alterations of the acyl chain packing.
Results described here are consistent with alterations in telomere function, providing a potential mechanism by which prolonged Raf activation is involved in regulation of cell growth and transformation.
Embryos from both 129/SvEv and B6.129 mixed backgrounds display craniofacial defects consistent with alterations to the first and second pharyngeal arches.
The changes in ADC and thus in water mobility are consistent with alterations within brain regions and are reflective of tissue remodeling that may include changes in microglia, astrocytes and axons within the affected region.
Similar(37)
We found regions of aberrant DNA methylation which were consistent with alteration of TGM-2, MMP-2, and CD24 transcript and protein expression, and that inhibition of methylation in cultured cells can increase the expression of these genes.
Changes in Ca2+ influx after the burst would be consistent with alteration in VGCC kinetics of inactivation and/or recovery from protracted stimuli.
Because our RNAi experiments are targeting the postsynaptic cell, our results are consistent with alteration of the GIT1/βPIX complex disrupting inhibitory postsynaptic domains, which also causes subsequent disruption of presynaptic innervation.
Such a mechanism involving CETP would be consistent with alteration of the particle size distribution of HDL towards larger, relatively cholesterol-rich particles that are characteristic of healthy low-risk populations manifesting the ideal profile of low TG and high HDL-C.
The approach we have used has previously been shown to reveal regional thalamic alterations that are consistent with focal alterations in thalamocortical connectivity [Hughes et al., 2012], and also corroborate the observation of thalamic changes using other morphometric approaches in patients with idiopathic generalized epilepsy [Kim et al., 2013; Saini et al., 2013].
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