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Our results are consistent with a critical role of slow waves for the beneficial effects of sleep on memory that is susceptible to natural environmental influences.
We use the antibody to demonstrate that linear polyUb is up-regulated upon tumor necrosis factor α stimulation of cells, consistent with a critical role in nuclear factor κB signaling.
However, these transporter genes were not differentially expressed between CO2 and O2; perhaps they are constitutive, which seems consistent with a critical role in rapid assimilation to a bicarbonate-rich environment.
Consistent with a critical role for this region in β subunit effects, there was no additional change in gluconate inhibition when the Δ6 20 mutant was expressed without β subunits.
The high levels of CXCL12 found in the primary tumour site (adrenal gland) and in a major site of metastasis in our model (the liver) support the notion that it may confer survival and proliferative advantages to the NB cells and is consistent with a critical role of tumour microenvironment in primary and secondary tumour growth.
This is consistent with a critical role of loop E in agonist recognition and a ligand-binding pose of serotonin that is nearly perpendicular to granisetron.
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Further, rad59Δ exhibits epistasis relationships with both msh2Δ and rad1Δ that are consistent with Rad59 playing a critical role in the removal of non-homologous tails [27], [36], [49].
These findings are consistent with models that assign a critical role to mimicry in the ability to develop and communicate empathy towards conspecifics, and provide a potential causal mechanism of effects of testosterone on empathy.
Consistent with protein structure playing a critical role, HJURP binding to CENP-A-H4 induces more compaction and less flexibility compared to a control condition.
These observations are consistent with other studies suggesting a critical role of the IgG Fc regions of anti-CD40L antibodies in mediating platelet aggregation [ 20].
These findings are consistent with previous reports indicating a critical role for efferocytosis in driving stromal wound-healing and remodeling events that contribute to malignant severity in postpartum breast cancers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com