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The most consistent trigger was alcohol intake.
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Maintaining a record sampling ratio from each health system that was consistent with trigger 1, we reviewed 669 of 14 777 visits selected by trigger 2 and 614 of 193 810 control non-triggered visits.
In all patients, pain could be elicited by tactile/mild sensory stimulation in different skin areas, consistent with trigger points that affect patients' QoL, preventing them from shaving, brushing teeth, kissing or washing their faces for fear of triggering pain.
Furthermore, in HaCaT cells higher siramesine concentrations induced cytochrome c release into the cytosol within 15 min, which is consistent with triggering the intrinsic apoptotic pathway.
Together, these data are consistent with the trigger hypothesis whereby NAADP provides the trigger Ca2+ from acidic stores that is subsequently amplified by IP3Rs on the ER [ 13, 19].
Strengths of this study are the strict headache diagnosis according to the ICHD-II criteria and the differentiation between consistent and occasional trigger factors.
Although consistent with the "trigger" ROS production described by Zorov et al [13, fig. 4C], it is far from being a systematic pattern.
But I should have actually probably got it seen to a lot earlier than I did.' Associating symptoms with cancer was a consistent help-seeking trigger.
The heights of the cosmic ray pulses are consistent with the triggering level set in the lightning observation mode, implying a normal condition of triggering logic and hardware.
Figure 3 shows examples of events that are consistent with onset triggering by tilted streamers that are not as ideal as the event in Fig. 1.
Fig. 3 Examples of events on 10 November 2006 and 13 October 2012 in the same format as Fig. 1 that are consistent with onset triggering by tilted streamers that are not as ideal as the event in Fig. 1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com