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In addition, the patient groups were defined by earlier or later inclusion, and unidentified time-dependent factors may have introduced bias, even though consistent standardization of procedures was feasible.
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In the remaining 10% of conditions, the prevalence between the two databases became less consistent after standardization.
In order to optimize conditions and achieve consistent results, standardization and quality assessment of all culture components is essential.
The terminology used in the following section is consistent with the standardization report of LUT symptoms and function by the International Continence Society and will refer to their definitions when appropriate [ 17].
Full-Scale IQ scores at 6 years of age were correlated with maternal IQ scores (r = 0.52, p < 0.001), and with the children's own scores on the Stanford-Binet IV, previously administered at 3 and 5 years of age (Canfield et al. 2003a) (r = 0.74, p < 0.001; and r = 0.82, p < 0.001, respectively), at magnitudes consistent with the standardization samples for these instruments (Sattler 2001).
Assessment of rotational laxity has now become standard practice in most institutions, highlighting the need for standardization and consistent documentation.
Popeyes is hardly an acquired taste, but even still the consistent familiarity of such standardization is a comfortable draw.
Standardization or consistent disclosure of measurement methods would greatly facilitate comparison and aggregation of data into larger data sets that can be used to monitor exposure and risk.
Consistent with the intended standardization, to contain 30% andrographolide, the content was on average close to this value (32.2 ± 2.1%, range 27.5 to 35.9%; n = 12; peak #12 in Figure 1B).
Based on pharmacological theory and confirmation that hematocrit standardization is consistent with unbound concentration-independent pharmacokinetics, we recommend that tacrolimus whole blood concentrations be standardized to a hematocrit (Hct) of 45%% (Cstd = Ctot × 45 %/Hct) to reflect the unbound (active) drug more closely.
For example, we see the prevalence of the concept of "Abdominal Pain" in CCAE goes up from 0.41% in the raw data to 0.50% within the CDM and the prevalence in the Optum data goes down from 0.50% in the raw data to 0.45% within the CDM, and the two databases have more consistent prevalence estimates after standardization to CDM.
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