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For the eight total genomic regions detected from at least three variables, no consistent specificities were observed across either environments or strains, except for the three regions that were more specifically identified from French field (Ae-Ps4.1 and Ae-Ps6.1) or controlled condition (Ae-Ps5.1) data.
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Most of them have reported high and consistent specificity but low and inconsistent estimates of sensitivity [12], [13], [15].
Relaxing the LRR threshold may have resulted in more false positives, but these seemed to be filtered effectively by downstream application of quality score thresholds, based on the consistent specificity.
Therefore, results of our interaction assays are consistent with specificity of Dock9 and Dock11 for Cdc42, and dual specificity of Dock10 for Rac1 and Cdc42.
The inset to figure 1 shows that binding of 213Bi-DTPA-[F3]2 to tumor cells can be blocked by an excess of unlabelled peptide consistent with specificity of binding.
It also keeps consistent high specificity with respect to different tumor impurity levels (<0.8) and sampled coverage.
FruMB exhibits the most consistent binding specificity, which we determined is dependent on amino acid residues that are required for DNA binding.
Both HIF-1alpha and HIF-2alpha are activated in close correlation with retinal hypoxia but have contrasting cell specificities, consistent with differential roles in retinal ischaemia.
This is consistent with the specificities of the enzymes and the proposed oligosaccharide composition of the IOS.
The expression of CD57 was more consistent across epitope specificities (Fig. 2 a and b, Fig S1b).
In comparison, expression levels of CD244 and LAG-3 were more consistent across epitope specificities (Fig. 2 d, Fig S1e and f;).
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