While these patients represent the target population for the final CD-PRO/SS, it is generally best to include subjects with a full range of disease severity in psychometric evaluation studies to optimize testing and assure consistent score performance across this overall range in severity.
Where there was greater that 10% discrepancy between the two results, reading was repeated until a consistent score was obtained.
This datum was partially due to a rapid and consistent score reduction of constitutional, lymphadenopathy, glandular, articular and cutaneous domains.
The longitudinal repeated measurements, such as the Bayley Scales and Copying Blocks, demonstrated consistent score increments as children aged.
During the trial, however, when a more consistent score became available based on separate diagnostic studies, we used the second score (score 2 (acronym FeverPAIN), n=631).
In those cases (<5%) in which the evaluation results of the two independent authors (CJ and NS) were different, the specimens were re-evaluated together and a consistent score was found.
