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The standardized fitness is used to have a consistent readout of performance of cells.
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The sensitivity of the method was demonstrated by accurate and consistent readouts from a controlled population of mutant genotypes.
For two subjects (1 and 3), feedforward stimulation did not lead to consistent informative readout in any of the six depths.
Although mouse phenotypes have been identified that meet these criteria (Table 2; supplementary material Tables S3 S7), some phenotypic domains, particularly those involving complex behaviors (e.g. social behaviors and anxiety), still lack consistent, reliable readouts in current RTT models.
Hence, the molecular signature imposed by miR-92 overexpression is consistent with its functional readout.
These HYPs failed to describe a consistent and plausible mechanistic readout of pro-inflammatory signaling.
To corroborate that the Wnt reporter provided a consistent Wnt-activated cell readout, antibody staining to detect cells harboring nuclear localized β-catenin was performed.
The data reported here cannot be explained by the inherent variability of the ELISPOT readout and are consistent with those from other, albeit small, studies from other settings.
tph-1 mutants showed increased encoding capability in all readouts while daf-7 mutants demonstrated consistently diminished fidelity, consistent with their respective effects on dynamic range and the variability of gene expression.
The behavioural readouts were generally consistent with earlier indoor experiments, but the changes and recovery were more variable and were not significantly influenced by sound intermittency and interval regularity.
The results between the duplicates for all readouts were clearly consistent.
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CEO of Professional Science Editing for Scientists @ prosciediting.com