In some cases we could observe striations with a consistent periodicity resembling zipper-like connections grouped into clusters, although there were large stretches of membrane contacts containing no visible linkages.
The area of the promoter upstream of the NDR shows high occupancy and weak, 'fuzzy' positioning (Lee et al. 2007), whereas the transcription start site marks the beginning of strong, consistent periodicity with well-positioned nucleosomes.
This finding suggests that energy generation during this period of embryogenesis displays periodicity, consistent with a circadian rhythm that may reflect the nocturnal activity of the mother.
Throughout this paper as well as part 2, we employ the following mathematical description of a tidal oscillation, consistent with the periodicity in time and longitude imposed by the Earth's rotation with respect to the Sun: A n, s cos nΩt + sλ − ϕ n, s (1).
This study reveals a periodicity consistent with a substantial α-helical character within the S2D4 segment in agreement with revelations from crystallographic studies of K+ channels [10], [28], [38].
Transplants of fetal SCN tissue to SCN-lesioned animals restore rhythmic behavior that is consistent with the periodicity of the donor's genotype [5], [6], [7], suggesting that the SCN controls the period of the circadian behavioral rhythm.
IPD incidence was greatest in the wintertime, and spectral decomposition revealed a peak at 51.0 weeks, consistent with annual periodicity.
The measured RDCs showed a periodicity consistent with the repeat structure of the AR domain; all of the helical regions exhibited RDC values between −5 and −10, whereas the variable loops and β-hairpins exhibited large, mainly positive values.
Interestingly, from a linear analysis of the number of apparent translational positions as a function of the length of the flanking DNA, we determined that a new position was observed for each ∼12 bp of additional flanking DNA; this spacing is consistent with the periodicity of histone DNA contacts within the high-affinity positioning sequence (∼10 bp).
In the latter study, DNase I digestion revealed a consistent 10 bp periodicity, with the minor groove at WW (W = A or T) dinucleotides facing the histone core and the major groove at SS (S = C or G) dinucleotides facing the histone core a half-period (5 bp) away.
We calculated the number of AA or TT dimers at each position along the length of the aggregated, complete set of reads, aligned at their starts, and we observed a ~10-bp periodicity consistent with nucleosome structure and previous deep sequencing analyses [ 7, 10].
