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All 7C8 residues were numbered according to the Chothia numbering scheme that compensates for length variability in the CDRs and generates a consistent numbering of the structurally conserved Fab framework region [35].
To address these issues, we have developed a consistent numbering scheme (see Methods) using the prototypic PKA as the frame of reference.
Despite the conformational change, we designated this elongated α-helix as α2/3 to maintain a consistent numbering scheme for conserved ESCRT-III helices.
In our structures, we have maintained a consistent numbering system for the water molecules, such that wherever possible an experimentally observed water molecule at a given position has the same number in all structures.
To maintain consistent numbering in NANOG and NANOGP8, all nucleotides in NANOGP8 were numbered according to their alignment with the inferred mRNA sequence in the alternate reference assembly for NANOG.
Rms deviations between all four Gal3C structures (Table S1) and the consistent numbering of water molecules in their active site areas (Table S2), electron density of the α and β anomers of lactose and hydrogen atoms, NMR spectra of histidine side chains, and ITC data, and NMR spectra of glycerol titrations.
Similar(54)
"It's tough when you haven't got a consistent number," he said.
"A consistent number of people involved with these studies got extraordinary sums," he said.
"There is a consistent number of people who have been affected directly because their loved ones have been affected by drug addiction.
"You didn't get this consistent number of weird situations that just came up, pretty much since the beginning of the year".
Until this season, Adam Dunn had fairly consistent numbers in the major leagues, including plenty of homers and runs batted in.
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