Our findings suggest that up to 18 IS families show patterns of orientation in chromosomes that are consistent with an interplay between IS transposition and host DNA replication.
The data we present are consistent with an interplay between MLL-AF4 and AF4-MLL through the regulation and function of RUNX1, providing a model of how these oncoproteins could cooperate on a molecular level.
Consistent with the interplay between these events, we identified several instances in which changes in methylation status (24 genes affected), miRNA expression (1 gene affected), or both (1 gene affected) are inversely proportional to our observed CBA-dependent changes in mRNA gene expression (Fig. 3).
Such a form of gene-by-environment interplay is consistent with a diathesis-stress model, and points towards gene-by-environment interactions [20], [21] that, while rooted in early life, can exert their effect also in early adulthood.
In addition, we identified a class of mutations affecting chromatin modifiers linked to transcription, consistent with a close functional interplay between condensin and the transcription machinery.
Both compartments also share many proteins with the cytoskeleton, most of which are involved in processes such as centrosome organization, chromosome segregation and nuclear division, which is consistent with the highly dynamic interplay between these compartments during mitosis (40).
The data are consistent with a fluctuating aeolian-fluvial interplay dominating the extended LGM environment with a greater impact on the landscape than all combined geomorphic processes since then.
On the other hand, the equilibrium structure of the system is obtained by the self-consistent mean-field theory (SCMFT) and the interplay between the "wetting" phenomenon and the phase separation is observed by modifying the property of the inner cylindrical wall.
But he has not found ways to finesse the meandering story line, hokey interplay among characters and woeful lack of consistent themes.
