At the same time point, this surface staining was reduced and partly interrupted in recombined Cre+Cdh1fl/fl mice, consistent with a disintegration of the intestinal epithelial lining (Fig. 3A and B, right panels).
It is important to note that annealing of h-BN films transferred to a 300 nm SiO2 /Si wafer support in air up to 700 °C did not lead to such a drastic disintegration consistent with recent reports.
The events of the past six months are consistent with a process of disintegration, while the process of integration has steadily weakened.
This phenotype is also consistent with the increased tissue disintegration seen in subcellular analysis of embryonic heart structure and by an increase in apoptosis in eMYH knockdowns compared with controls.
The Eudragit FS coated tablets that did disintegrate exhibited consistent intra- and inter-subject performance, with the site of disintegration focused on the ileo-caecal junction and ascending colon.
With the increase of drying wetting cycles, the percentage of the water stable aggregates in the size range of 5 10 mm decreases obviously and the initial two cycles has the most violent effect on the disintegration of aggregates, which is consistent with the result by Denef et al. (2001a,b).
The 10 wt% KCl solution has a good inhibitive effect on disintegration and micro-fractures, which is consistent with the results of CST tests, as shown in Fig. 16.
In contrast, the inner epithelia had more consistent p63 expression and were less prone to disintegration.
Consistent with this, we observed the most efficient disintegration activity with SsoCas1 when substrates had a guanine at the +1 position.
