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The consistent direction of allelic effects suggests a history of directional selection on the posterior lobe.
MiRNAs were ranked on the basis of criteria as: (1) number of the studies that consistently reported the miRNA as differentially expressed, (2) the consistent direction of change of differentially expressed microRNA, and (3) total number of samples for comparison in agreement.
Here the genius of Holmes was first clearly revealed and the consistent direction of his thought made evident.
As a result, the euro area's GDP per head has in fact grown at the same pace as America's.Discounting the obvious explanation that American statisticians are born optimists, it is unclear what lies behind the consistent direction of these revisions.
Family history was not associated with younger age at onset for any disorder.Associations between family history of a disorder and clinical features of that disorder in probands showed consistent direction of effects across depression, anxiety disorder, alcohol dependence, and drug dependence.
When samples are shuffled and consistent direction of change is lost, existing memories do not update.
In all cases, the consistent direction of perceptual drift underscores the brain's apparent tendency to consider some stimuli to be special reference points, or norms.
Because we required evidence of replication with consistent direction of effect in a second dataset, we did not require a stringent multiple testing correction.
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These data identify a novel DKD susceptibility locus with consistent directions of effect across diverse ancestral groups and provide insight into the genetic architecture of DKD.
Interestingly, rs1250248 in FN1 showed a strong association with Stage III/IV disease (P = 8.0 × 10−8), had consistent directions of effect across all studies and populations, but just fell short of the genome-wide significance threshold.
Inspection of all of the other biases shared between two or more accessions found strong, consistent directions of homoeologous expression bias suggesting that the bias has roots in the independent evolution of the two progenitor species prior to reuniting within the common tetraploid nucleus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com