Your English writing platform
Discover LudwigSuggestions(1)
Exact(10)
To determine genes consistently linked to COO class we used both the consistency of differential expression between data sets as well as absolute level of differential expression to identify and rank genes associated with each class.
Figure 2 illustrates a link between consistency of differential expression in transition from norm to cancer and expression variability in the norm.
Figure 1 presents normalized levels of expression, consistency of differential expression and integrated panel variability for 54675 probe-sets comprising the high density U133 Plus 2.0 microarray platform by Affymetrix.
The absolute expression levels were also positively correlating with consistency of differential expression detection.
To address whether the consistency of differential detection between data sets would alter this conclusion we ranked genes by a measure derived from both the number of data sets (consistency of differential expression) in which a gene was differentially expressed and the normalised median fold differential expression (Additional file 12).
The microarray quality control (MAQC) project was established to explore inter-platform and inter-laboratory consistency of microarray-derived gene expression datasets using two reference RNA samples [ 11], as well as consistency of differential expression estimates [ 12, 13].
Similar(50)
To further investigate the consistency of the differential gene expression levels within subgroups, we clustered the expression ratios of the genes in Wnt signalling pathway in GBM.
Validation was performed in two different ways to assess both the hotspot nature of the FEM modules in the independent data and also to assess the consistency of the differential methylation and expression statistics across studies.
To check the general consistency of the differential expression analysis results obtained in our study using RNA-Seq and in the study of Costantini et al. [ 13] using microarrays, we considered the direction of change (if detected) for each of the genes that were included in the RefSeq annotation for RNA-Seq (n = 24,628).
Although this topic received a flurry of attention in the 1980s, Krueger and Summers (1987) and Krueger and Summers (1988) established the consistency of these differentials over time and across countries, the fundamental question remained unresolved: are these differentials due to individual or employer components?
Unfortunately the relatively small degree of legitimate biological differential expression between the pre-and post-treatment tumour biopsies provided little opportunity to assess the relative performance of UHRR and pooled batch calibrators on the consistency of reported differentially expressed probes.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com