Male Wistar rats (250 300 g) were exposed to HAL (2.0 mg/kg/day), RISP (2.5 mg/kg/day), or CLOZ (20 mg/kg/day) for 45 days or a pre-treatment regimen consisting of administering either RISP/HAL (i.e., RISP followed by HAL) or CLO Z/HAL or a post-treatment regimen consisting of administering: HAL/RISP or HAL/CLO Z
Treatment A consisted of administering the nutritional supplement according to label directions (100 g in 1.9 L of warm water, 3 times a day), and treatment B consisted of i.v. LRS (2 L, once a day).
Treatments consisted of administering, for 14 d, a daily gelatin capsule containing no B-vitamins, 10 mg of biotin, 240 mg of pantothenic acid, and 10 mg of biotin + 240 mg of pantothenic acid.
The torture consisted of administering agonizing jolts of electricity with a hand-held device that could deliver charges of up to 40,000 volts in an effort to force confessions from the four suspects in separate cases at the station house in Ozone Park.
Treatment of poisoning largely consists of administering 100% oxygen or providing hyperbaric oxygen therapy, although the optimum treatment remains controversial.
In order to increase the sensitivity of our method and to avoid potential artifacts, we pursued an established strategy for indole detection consisting of administering an oral load of tryptophan, the aromatic amino-acid precursor of indoles.
