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This work is based on a new strategy in which analog advantages such as low die area, high speed and simplicity are added to the system advantages, whose output is digital considering unchanged digital system properties.
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In this sense, all the pixels whose intensities are within ± Nσ of zero are considered unchanged.
The region where the values of MDI are less than T M −δ 1 is considered unchanged class.
Total PEEP was considered unchanged if its value increased up to 1 cmH2O, which represents the accuracy level of the pressure measurement.
According to this observation, the desired set of pixels with a high probability to be correctly assigned to one of the two classes, i.e., certainty regions, is constructed as follows [4, 31]: (1) The region where the values of MDI are less than T M −δ 1 is considered unchanged class.
230 miRNAs (60%) were reliably detected on the array (Supplementary Table S1) of which 35% were considered unchanged as their expression levels varied only up to 15% from untreated controls.
Values between 1 and -1 were considered unchanged protein expression.
Patients were considered unchanged if they were neither improved nor worse.
The expression of a given gene was considered unchanged if it was similar to native adult RPE expression.
The protein intensity values were transformed with Log2, and normalized with the values at 0 min. The proteins with normalized values (≥ 2 and ≤2) were considered unchanged.
Where errors are shown, results are means ± SD. aValues for some patients remained above the upper limit of the assay (1,300 pg/ml) and were consider unchanged.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com