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Considering the time points of post-treatment F-FDG PET/CT scans, recurrences occurred in 27 patients at ∼3 6 months (range, 2 9 months) and in 27 patients at 12 months (range, 9 20 months), of whom 12 had recurrences at both time points.
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This analysis shows that considering the time point of maximal drug effects is helpful to improve prediction accuracy.
However, similarly to using prognostic indicators, considering the time point when co-morbidities cannot be treated might be too late in the disease trajectory to provide proactive palliative care as the cognitive abilities of a person with dementia have declined too much so that the person is no longer able to participate in the decision making process and advance care planning.
Designers of oncology studies should carefully consider the time points at which HRQL is measured, in order to ensure accurate estimates of HRQL can be made both pre- and post-progression.
The increase in accumulation of autophagy genes and of members of the inhibitors of apoptosis is not surprising considering the time-point, 5 h PBM, sample here.
For biofilm assays, one must also carefully consider the time point of biofilm sampling relative to the time point of starvation (carbon, nitrogen or oxygen) to properly interpret the results.
The time point of the second Villalta score of ≥5 will be considered the time point of PTS diagnosis.
One of the recommendations is to consider the time point of the diagnosis of dementia as the starting point of palliative care [ 12].
Professionals in two nursing homes considered the time point that curative treatment for co-morbidities is futile and does not improve the person's quality of life as the starting point for palliative care.
At this regard, it is important to consider the time point we analyzed (3 days after the end of all treatments), as the results could vary at different observation times.
The animals were killed 2 h after formalin injection for the analysis of c-fos activation, since this is considered the time point of maximal expression of the proto-oncogene (Coggeshall, 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com