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Although encouraging, the significance of this type of analysis is open to interpretation considering that many of the proteins are linked to cancer by as few as one reference, and further, it is not unexpected to detect cancer-related proteins by analyzing cancer cells.
False negatives (i.e. failures to detect mutations that are actually present) can result in erroneous interpretation, especially considering that a single mutation can have a dramatic impact on phenotype.
Therefore, I consider that any interpretation of this profile, which would be done by ignoring the confounding factors cited above, is abusive.
Apparently, it pays for consumers of controversial news to take a moment and consider that the opposite interpretation may be true.
There are some study issues to consider that affect the interpretation of our results.
We consider that the simplest interpretation of this unexpected observation is that expansion precursors are generated during the processing of Okazaki fragments, where both 3′ and 5′ ends are present.
We consider that the different interpretations and misunderstandings were clarified in the workshop, and the final advice provided in the Policy Briefs is robust.
Has the writer of that article, Lee Jenkins, ever considered that a more realistic interpretation is that Alfonso's leading vote count "obviously" relates to his endearing himself to Yankee fans when he played in New York?
We consider that as a valid interpretation, as there was no change of the transcript count per nucleus between those two cells.
Following this interpretation, we consider that knowledge mobilization is beyond the role and nature of the nodes and we treat KnowledgeNet as a homogeneous network of knowledge mobilizers.
Another interpretation would consider that the level of cytosine hydration is most likely reduced in the active site of the polymerase relative to DNA in solution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com