There is a relatively strong rationale for considering the use of steroids in patients with refractory septic shock.
This weight of evidence provides a strong rationale for considering antioxidants as a potential therapy for pre-eclampsia.
A recent article by Huang, Li, Armstrong and Harari provides strong rationale for considering the anti-EGFR agent ZD1839 ('Iressa') as a radiosensitizing strategy.
There is also a strong rationale for considering the NCDs collectively, since they share common risk factors and common interactions, i.e. between obesity, smoking and exercise, and diabetes, hypertension and cardiovascular disease.
While influenza vaccination remains the most effective means of reducing influenza-related morbidity and mortality, the risk of influenza and pneumococcal disease co-infection in a pandemic, along with the ability to vaccinate individuals prior to the onset of a pandemic, provide strong rationale for considering pneumococcal vaccination in the context of influenza.
As observed in the CTEP/NCI review process of early clinical trial proposals, robust preclinical data generally provide strong rationale and are considered to be of high priority for clinical evaluation.
Considering the characteristics of this study, there seems to be no strong rationale supporting the use of an abduction device in growing children.
However, there remains a strong rationale for the addition of radiation therapy considering the high rates of microscopically incomplete resections after surgery.
I think there was a pretty strong rationale, given the credit squeeze, of trying to put cash in businesses' pockets.
There is a strong rationale to study combinations of agents in vivo to guide clinical studies.
There's a strong rationale for that realism.
