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Selection of drugs for adding to list is performed in IDSC by considering of efficacy and safety, rationality in use, accessibility, and affordability altogether.
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25 In the BENCHMRK-I trial, considering lack of efficacy as treatment failure, HIV-1 RNA levels below 50 copies/mL were achieved in 79.5% of patients who received raltegravir compared with 42.5% of placebo recipients.
As noted above, ChEIs are considered of equivalent efficacy, with tolerability considerations guiding clinicians in their choice.
In many cases of HAT there are fewer than 100 parasites mL−1 of blood, and serological and molecular tests are not considered of sufficient efficacy to offer positive diagnosis.
Alternative treatment options, such as ER antagonists (e.g. tamoxifen ) and ER down-regulators (e.g. fulvestrant [FULV]), are considered of limited efficacy within the frame of endocrine resistance that occurs after first-line treatment with aromatase inhibitors [ 13, 14].
Thus it may be useful for commissioners considering how to implement NICE low back pain guidance [ 1], but cannot be considered proof of efficacy of the service.
Moreover, experts in the field considered determination of efficacy in PP difficult [ 27, 28].
Observing a statistically significant difference in mean HbA1c between groups at 24 months will be considered evidence of efficacy.
The efficacy and safety results of a TES should generally be reported together; abstract selection committees and journal editors should carefully consider reporting of efficacy alone before acceptance.
α is the accepted probability of considering adequate efficacy of the treatment with a true PFS-3yR equal or lower to p0.
In the present trial p1 has been taken as 70% α is the acceptance probability of considering adequate efficacy of the treatment with a true LC-5yR equal or lower to p0 (false positive decision).
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CEO of Professional Science Editing for Scientists @ prosciediting.com