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Spontaneous tumor regressions are among the rarest and most mysterious events in medicine, with only several hundred cases in the literature that can be considered well documented.
A large amount of information in free text is available that modifies the coded date or discloses incorrect classification as a case, even for 'hard' outcomes such as ovarian cancer, which is considered well documented in primary care records.
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Among the questions asked on the Dementia Risk Assessment are whether a person has a history of high blood pressure, depression, diabetes, high cholesterol or head injury, all of which are considered well-documented risk factors for dementia.
Considering the well documented negative effects on newborn infants we also believe systemic pethidine should be avoided in labour" [ 8].
Considering the well documented role of TRAF6 signaling in RANK-mediated osteoclastogenesis [ 15], it may, therefore, be hypothesized that TRAF6 is involved in differentiation of osteoclasts in RA.
Most importantly, the fusion scenarios referred to above underestimate the importance of phagocytosis; the hypothesis of engulfment of an α-proteobacterium ancestor in the capacity of mitochondrial precursor by a phagocytic protoeukaryote has lost none of its appeal, considering the well documented occurrence of prokaryotic endosymbiosis in eukaryotes [ 31, 47, 94, 95, 109, 110].
The desk review considered well over 100 documents relevant to the project, most of which were shared by UNICEF or independently-researched (See Annex V).
It also urged the UK government to consider the "very well documented and serious human rights abuses being conducted by the military regime in Egypt", and warned the UK government that it should not allow the review "to be seen as an endorsement of the criminal acts which continue to be perpetrated against the people of Egypt".
Although they are not about VMPs, these publications are also considered because they are well documented (e.g., measured redox potential) and conducted similar to transformation studies with VMPs.
To analyse the DC fault behaviour, an equivalent circuit of a half bridge MMC is shown in Fig. 1, and a number of stages can be considered which has been well documented in [25].
Moreover, it seems unlikely that bona fide cases of personal harm could be well documented considering the pattern of use and exposure levels of our customers".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com