Sentence examples for considered the expression profiles from inspiring English sources
Ten potential binding partners of the Dvl2 PDZ domain predicted by Tonikian et al. are not found in the prediction list of Stiffler et al. In addition, because neither study considered the expression profiles and subcellular localizations of the proposed PDZ-binding partners, the number of real binding candidates for a specific protein is expected to be significantly lower than that reported.
We also considered the expression profile of phosphatases in the four GBM subgroups described by TCGA.
Consider the expression profiles of two genes A and B under N perturbations (see Figure 1).
Most eQTL studies consider the expression profiles of different genes as different traits to be mapped one by one separately.
Given the importance of this dataset, we have analyzed the data with systems biology approaches considering the expression profiles of gene groups instead of individual genes.
Considering the expression profiles of genes assigned to the "response to auxin" category, the effect of the auxin treatment was quite small irrespective of the cultivar, and was mainly restricted to earlier time points (Fig. 5b).
To perform feature selection the average difference in correlation (calculated for each edge in a network by considering the expression profiles of the protein-pair joined by the edge) for each hub sub-network over the two groups of interest was calculated.
This observation led us to consider the expression profile of miR159 revealed by the H-T sequencing result rather than the one revealed by the qPCR.
On one hand, considering that averaging the expression profiles of all pathway member genes (that is, Mean all) results in the lowest accuracy, it is remarkable that simply removing half of the genes with lower t-statistics (that is, Mean top 50%) leads to the highest accuracy.
Therefore, to produce a single expression profile for each cell type whilst avoiding the production of similar expression profiles as a result of uneven cell-type representation, we considered the similarity of the expression profiles of the samples within each facet.
In this work, our method mainly considers the case that the expression profiles of TFs provide information about their activity levels, although other kinds of regulation (e.g., phosphorylation) can be added into our method if data are available.
