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These mutations were considered not functional because of the lack of any phenotypic effects.
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In some circles, it is considered not just functional, but an essential bit of modernity, like knowing what happened on "The Sopranos" or that Diesel refers to jeans, not fuel.
Indeed, our inquiry needs to be informed by considering not just the functional, but the symbolic importance of both the mouth and the anus in human lives.
It appears unlikely that the cluster is not functional, considering that it is highly conserved (> 58% identity, 75% positives between the three examples of the swf cluster) in the symbiotic microbiota of two taxonomically distant genera of sponges such as Plakortis and Aplysina.
For genes of 'unknown function', the putative function was further investigated using BLASTP software, but they were not considered for functional analysis.
The remaining bigger portion of human genome was not functional and being considered as "junk DNA" [ 2, 3].
Finally, the slight accumulation of p53 protein in JURKAT cells, although not functional, can be considered as a further phenomenon that supports the induction of a cellular response to DNA damage.
The main focus of this work is to ensure that the supervision of a function, performed by a safety critical embedded automotive control system (controlled systems are not considered), respects functional and safety requirements.
Also in our method, within a functional linkage graph, non-neighbors (two nodes whose distance are more than one) are not considered for functional similarity.
Sequences with no such significant hit were not considered in functional analyses (74% of viral data set and 50% of larger comparative data set).
The branches of pathways containing genes that are not expressed on microarrays were not considered functional.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com