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When no measure was available within 180 days of diagnosis, the data were considered to be missing; the exception was BMI, for which data were considered missing when no observation was available within 365 days of diagnosis.
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The total score was considered missing (invalid) when more than four items were missing.
The data set, respective alignment length including outgroup, number of sequences in data set excluding outgroup, number of haplotypes excluding outgroup, and number of variable sites excluding outgroup, when gaps are considered missing data, except for the mtDNA data set are given.
However, when analysing the data, we also considered missing information on treatment outcome just as missing data which do not necessarily imply default.
In the case of missing data, the mean was calculated when two or more scores were present, otherwise the variable was considered missing for that case.
When a response was "don't know" or "decline to answer" or "N/A" it was considered missing.
Gaps were considered missing.
When more than five items were missing among the satisfaction items or among the importance items, the entire QLI was considered missing.
Possibly, some did not feel comfortable answering both items about sexual and sentimental life, but the score of this dimension was considered as missing when at least one item was not answered.
When considering missing data we found that completion of the SOBDA daily e-diary, measured by data transmission, exceeded 90%% indicating that patients were able to use the e-diary over an extended study period.
When profiles were considered that only contained timing errors the RF was 0.80 and when only considering missed doses (random missed doses and drug holidays) the RF was 0.44.
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CEO of Professional Science Editing for Scientists @ prosciediting.com