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When an individual organism (O) affects the stimuli in any way for example, by thinking about a response the response is considered mediated.
The specific effects triggered by polypeptide hormone/growth factor stimulation of mammary cells were considered mediated solely by receptor-associated signaling networks.
The physiological effects of estrogens have long been considered mediated by a single nuclear receptor (estrogen receptor α [ 1, 2]) through which the signal is transduced to the transcriptional machinery and chromatin template of target responsive genes.
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In this paper we consider mediated interaction, which might be seen as intuitively more difficult, and so far lacks an easy-to-understand clinical or biological interpretation.
These pathways all act through SMAD proteins and are considered SMAD-mediated TGF−β signaling pathways.
No reviews considered patient-mediated interventions in isolation from other strategies, although four considered multifaceted interventions that included them.
No other events that could be considered immune-mediated were noted in children with and without ADA.
We considered RNA-mediated duplication (retrotransposition) per se as an event contributing to the birth of pseudogenes.
Patient decision aids were considered patient-mediated interventions because one of their purposes is to foster patients' participation in decisions made during the clinical encounter.
MPGN cases that present clear glomerular C3 staining with absent or scanty immunoglobulins are considered complement-mediated MPGN and are referred to as C3Gs (Fig 5).
As KOP receptor agonists are aversive, we considered KOP-mediated antinociception might be a form of stress-induced analgesia that is blocked by the anxiolytic effects of DOP receptor agonists.
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