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Microbial extracts from P3-86A, P3-37B and K18 showed <10 fold increase in caspase-3/7 activity and were termed as active (in the range of 1.7-6.0 1.7-6.0while extracts foldsChromohalobacter salexigens (K30, P3-86B(2)) and Idiomarina loihiensis (P3-37C) whileconsidextractshly active due to their remarkably high caspase-3/7 activity (≥50 from inChromohalobacterred to untreated cellsalexigens
Plant alkaloids like docetaxel and paclitaxel are considered highly active chemotherapeutic agents in various cancers including those of the breast and prostate [ 4, 5].
Based on this criteria, only the extract from Atractylodes lancea is considered highly active with IC50 of 24.04 ± 3.40 (mean ± SD) μg/ml.
The response rate observed for urothelial cancer in our study is within the range of the responses seen with other conventional (Sternberg et al, 1989) and newer schedules (Von der Maase et al, 1999; Dreicer et al, 2000) which are considered highly active.
Male rats that achieved ejaculation in each of the three tests in less than 30 min were considered highly active, those that achieved ejaculation in one or two of the three tests in less than 30 min were considered moderately active, and those that failed to achieve ejaculation in any of the three tests in less than 30 min were considered sexually inactive and excluded from the study [ 10].
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