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To our knowledge though, although such scaling trends have been considered for animals operating in water and air (Domenici, 2001; Hedenström and Rosén, 2001), this has not been explicitly examined in the literature for terrestrial animals.
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Further, the scaffold with both HA and bioactive glass was considered for the animal study.
The value considered for each animal was the mean of 5 consecutive measurements.
The authors believe that the procedures taken were extremely robust, and suggest that such approaches be considered for companion animal RCTs in the future.
The submesothelial thickness was determined in a blinded manner, by microscope analysis and the mean of independent measures every 60 μm was considered for each animal.
After computing the width of individual action potentials, we considered, for each animal and each stimulus, only pairs of cells that exhibited oscillatory activity and were synchronized to make sure they participated in the same oscillatory process.
These characteristics were those considered for grouping the animals.
Only CT findings were considered for group allocation: animals with lung opacifications other than small, localized dorsal atelectasis were included in the respective opacified group.
Therefore, a comprehensive number of cytotoxicity studies involving mammalian cells or tissue cultures must be conducted before a given extract or a defined Rhododendron-derived compound can eventually be considered for testing on animal models, or even enter clinical trials [ 53, 54].
Glyphosate, a post emergent herbicide, has become the backbone of no-till agriculture and is considered safe for animals.
For sensitivity estimation all animals under study were considered, for specificity only negative reference animals and for PPV and NPV estimation both cases and negative reference animals were used.
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