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For a chemical to be considered active in a pathway, it had to have shown activity in at least five assays that mapped to that pathway.
When re-tested in a qualitative visual assay of PED-6 metabolism, 15 of these compounds were considered active in a dose responsive fashion (0.3% of the total number screened).
However, many sources of exposure to such chemicals, especially those that are not considered "active" in a given product, are unknown.
Similar(57)
The regimen was considered active in the treatment of these malignancies, as a 37% objective response rate and a very high disease control and symptom control rate were recorded.
In the non-GIST group, this PFS is in the range of other agents considered active in STS, and may predict for more substantial first line activity.
They represent the mean number of UEs considered active in the corresponding link per TTI, calculated over one measurement period (2 s) and normalized by the cell bandwidth.
Of the patients studied, 70% received at least one agent considered active in vitro and most patients received at least three concomitant antibiotics.
Each compound was assayed at the highest concentration deemed inactive and the lowest dose considered active in the visual dose response experiment.
Several chemotherapy agents are considered active in advanced gastric cancer.
These concentrations were too high to be considered active in this study.
However, chemotherapy is generally considered active in poor-differentiated NENs (with response rates 50% ~ 70%) [ 33- 35].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com