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The ability to reproduce past events is considered a stringent test of the merits of any geological model.
The inhibitory action of HB-19 on tumor cell replication was evaluated in soft-agar colony-forming assay where inhibition of colony formation is considered a stringent test of the anticancer activity of a compound.
Though considered a stringent "intrinsic" molecular subtype definable by presence of steroid receptors, luminal breast cancer is a complex disease.
Moreover, they inhibit colony formation in soft agar, which is a hallmark of the transformed phenotype of cancer cells and considered a stringent surrogate for in vivo tumour formation [ 51, 52].
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Contrary to Analysis 3, in Analysis 1 and Analysis 2 the moderated t-test statistics implemented in Limma considering a stringent significance threshold of an FDR adjusted p-value of q ≤ 0.05 were applied.
The effect of clearance (C) on the flow patterns in stirred vessels was simulated as the flow field transition observed can be considered a particularly stringent benchmark for the testing of CFD techniques.
Entering the pluripotent ICM lineage is considered a more stringent test for naïve state ESCs (Gafni et al., 2013; Takashima et al., 2014).
Secondly, we considered a more stringent measure of the error by looking at the supremum of difference between the same range of avalanches Error ( N ) = sup n | P e ( n ) − P k ( n ) |. Figure 5 illustrates the two errors for increasing network size and both show how the proposed closed solution is indeed converging to that of the exact.
Therefore, we considered a more stringent significance level of α=0.001 (10−3) relative to the number of performed test in the range of 10.
MACE is considered a more stringent end point with arguably less ambiguity and bias and more certain ascertainment than some "softer" end points.
The use of anti-asthmatic medications may be considered a more stringent outcome definition, identifying only the most serious cases; in the MCS only children taking daily medications in the last 2 weeks are identified.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com