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All of these considerations are true in critical illness, but there are even more potential confounders such as inflammation and acute fluid loading that may affect vitamin D concentrations.
These considerations are true irrespectively of how fast the target-search is, and are important for the understanding of the nuclear architecture and its influence on regulation of gene transcription.
But, shifts in resource or habitat are probably less common than previously expected, as shown for sawfly larvae and caterpillars [ 95, 96], and all aforementioned considerations are true for exogenous but not endogenous insect toxins, because these are per se unrelated to host affiliation.
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However, this consideration is true if the DNA under consideration is actually coding.
Similar considerations are also true for metastatic breast cancer, where tumor samples may be limited to tissue from the primary disease site, which again, may be separated from disease recurrence by both time and treatment [11].
These considerations are especially true in Japan, where hospitals typically underutilize critical patient safety practices.
These considerations are mainly true for those tumors that appear hyperechoic by comparison with surrounding brain, for example, metastases, high-grade gliomas, lymphoma, and, in particular, meningiomas [ 37– 37].
These considerations are also true in the PMSI: overreporting was estimated at 11% for cancers of the thyroid in a study based in 10 districts (28 ) and at 15% for mesothelioma (29 ).
Similar considerations may be true for the mixed alkali content of the flakes I/3, I/39, I/60 and I/62.
Similar considerations may be true for North European and English glass production, where lead glass is reported occasionally for the Middle Ages [12, 13].
Gladwell mostly neglects such considerations, despite their being essential to the question at hand; namely, whether the charges are true.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com