The inclusion of sequence-dependent intrinsic curvature also leads to nonuniform twist and necessitates consideration of eight distinct binding topologies from the known crystal structure of the LacR-DNA complex.
An important characteristic of 3-D similarity methods, compared to 2-D similarity methods, is that 3-D similarity methods are applied at a conformer level, not at a compound level, to enable consideration of various distinct molecular conformations in 3-D space that may be biologically relevant.
Although the divergences were less against B5, B8, B7 and B3 (3.43 ± 0.25, 3.22 ± 0.24, 3.21 ± 0.31, and 3.07 ± 0.24, respectively), we argue that consideration of the distinct geographical and host ethnicity association [ 21], in addition to the phylogenetic and genetic distance data, define the unidentified cluster as a distinct subgenotype.
It is often assumed that waste separation at source can be had 'on order' by developing country city authorities simply through a donor-driven project, without thorough consideration of the significance of distinct socio-political contexts commonly encountered in Third World societies that immensely vary with those found in mature liberal democracies.
Due to difficulties controlling LSDV by vaccination in the Horn of Africa and the Middle East (Ayelet et al., 2013; Brenner et al., 2009; Tuppurainen, 2006), and taking into consideration the distinct threat of incursion of all CaPV diseases to Europe and Asia, a new generation of effective and safe vaccines against LSDV, SPPV and GTPV are urgently required.
The dispersal pattern of 63 Arabidopsis LRR-RLKs with well-defined roles prompted consideration of the ancestral role of distinct PtLRR-RLK subfamilies and there is a possibility that PtLRR-RLKs belonging to distinct subfamilies perform certain functions in different developmental aspects.
Since we would like to consider the initiation of seizures in the whole brain, consideration of the interaction between distinct cortical regions is an appropriate level of description for the model.
This relationship between current training and future burdens on the poor law is characteristic of the consideration of pauper children as distinct from waged child labourers or the non-poor.
Because GS was designed for a general problem of peptide-protein binding prediction, it did not take into consideration some distinct features of MHC-II binding peptides.
Each of these factors will guide wildlife disease ecologists to take into consideration a distinct set of ethical questions, articulated through the language provided by the six core values, and with attention to adaptive management and EER.
