Sentence examples for consideration of binding from inspiring English sources

Consideration of binding competitiveness of a drug candidate against natural ligands and other drugs that bind to the same receptor site may facilitate the rational development of a candidate into a potent drug.

As discussed above, consideration of binding and unbinding between singly- and doubly-bound desensitized states improved the fit of our data.

However, it has recently been suggested that selective pressures on proteins to avoid non-specific binding are also an important aspect of protein fitness, necessitating consideration of binding "decoys" as well [ 14].

The second method, MultiBind [ 58] is based on recognition of similar physico-chemical properties of the protein binding sites without any consideration of the binding partners.

Although the structure of the FR invites consideration of cooperative binding of EBNA-1 (and/or Oct-2+Grg/TLE) to these binding sites, no experimental data is at present available.

Comment: 4) As far as I can tell, there is also no consideration of peptide binding register (where the peptide is positioned with respect to the binding pockets).

This review outlines recent methodical advances in homology modelling, with a focus on those techniques that necessitate consideration of ligand binding.

With consideration of Kubas binding as a viable mechanism (along with hydride formation and physisorption to carbon support) the role of hydrogen spillover in this system may be smaller than previously thought.

In consideration of surface binding, one hypothesis is that apoptosis might result in translocation of intracellular antigens to the external leaflet of the membrane.

Some aspects of dynamic modeling of statins have been tackled in previous studies, including the deterministic modeling of transport kinetics [ 33, 34] and the pharmacokinetic modeling of the clearance mechanisms including consideration of unspecific binding effects [ 35].

These values were slightly increased compared to those in our previous study, due to the updated model's consideration of GRB2 binding to EGFR, which protects EGFR phosphotyrosines from dephosphorylation.