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Under the assumption that the random marker loci in our study are unlinked to the polymorphisms controlling the expression of the traits under consideration, association mapping methods that adhere to the nominal α level show a uniform distribution of P values, i.e., a MSD value close to zero.
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Taking into consideration the association of BRINP3 rs1935881 and rs1342913 polymorphisms and the occurrence of peri-implantitis, we analyzed the association between BRINP3 markers and peri-implantitis in the replication sample based on groups divided according to peri-implant status (Additional file 4).
After much consideration, the association let its invitation stand.
Taking into consideration the association of Cdk5/p35 with cytoplasmic organelles, including early and recycling endosomes, Cdk5/p35 may also participate in vesicle transport.
Another important consideration during association mapping is population structure.
However, few researches take gender difference into consideration in association analysis of susceptibility gene.
Taking everything into consideration, the association between vitamins B/physical activity and depressive symptoms remains unclear among university students.
Such genomic variation in LD must be taken into consideration during association analyses (Ersoz et al. 2009).
The Mixed Linear Model used to detect associations between markers and traits allowed population structure and relatedness to be evidenced within our collection, which have been taken into consideration for association analysis.
As stressed by Kreisman and Hennessey [ 14], frankly abnormal serum creatinine levels may occur in some cases of hypothyroidism and not taking into consideration the association of thyroid metabolism and glomerular filtration rate may lead to unnecessary and costly investigations.
As the estimated age for the whole of haplogroup U6 is around 35 kya, this removes the Aterian from consideration for association with the genetic signal for dispersal in North Africa [ 8, 9].
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