Sentence examples for considerably upstream from inspiring English sources

As PMX464 prevented TNF-α-and IL-1β-induced IKK andinity and, in general, IL-1β and TNF pathways vary considerably upstream of IKK, this would suggest that PMX464 acts in close proximity to IKK.

In this study, as discussed previously, the changes in SEA are mainly determined by CR which decreased considerably from upstream to downstream.

However, the inserts in the current study were located considerably further upstream of any known RIPK1 exon.

Similarly, the standard ellipse area (SEA) size was greatest at upstream and decreased considerably at midstream and downstream.

Among them is the potential to scale upstream expression with considerably lower capital requirements compared to traditional cell culture processes.

Acetylation of the tested lysine residues on the upstream promoter differed considerably from core promoter acetylation as it correlated well with transcription levels.

However, unlike nucleosome-depleted regions that are generally localized to core promoters and enhancers, H1 displacement is considerably more extensive, extending significantly upstream and downstream of the transcription start site (TSS) [ 7– 9].

These results suggest that gene expression at this genomic site is not considerably biased by either the upstream or the downstream genomic elements, and that the neighboring genomic regions do not significantly influence the behavior of pGAL1 and pKlURA.

In other broadband mediums, the upstream speed can be considerably slower than downstream.

Sequences upstream this core vary considerably among the various family members in length and sequence.

The injured capillaries are highly permeable vessels and their recruitment may considerably increase fluid and protein leak upstream of the obstruction.