Sentence examples for considerably lower doses from inspiring English sources

Certainly bus riders or hotel workers would receive considerably lower doses.

The drug concentrations employed in this assay showed no direct toxicity on macrophages, while they drastically reduced the association index at considerably lower doses than those required to interfere with promastigotes.

Compared to the lung and breast, most sites probably receive considerably lower doses of radiation.

Under conditions of low physiologic estrogen exposure, as is the case during prepubertal development as well as after reproductive senescence, considerably lower doses of BPA may be sufficient to interfere with the synaptogenic effects of the hormone.

Analogues of curcumin, such as HO-3867 are taken up by multiple drug resistant or sensitive cancer cell lines at considerably lower doses than curcumin [ 83], while synthetic analogues, G0-Y030, FLLL-11 and FLLL-12 promotes anti-proliferation in colorectal cancer cells at lower IC50 than curcumin [ 81].

Although K-877 has not been compared with fenofibrate in head-to-head studies, it is approximately 10,000-fold more potent than fenofibrate in vitro[ 52], has a greater lipid-modifying efficacy at considerably lower doses both in animal models for obesity/T2D and in humans, and is associated with an improved safety/tolerability profile [ 50- 52].

Endocavitary CEUS differs in that the volume of the solvent, the fluid within a cavity, is much smaller than the volume of circulating blood in the vascular tree, and a considerably lower dose of UCA is required.

αCGRP infused in a considerably lower dose (0.6 μg/min) did not change MCA velocity or rCBF in healthy volunteers [21], while the dose of 1.5 μg/min in volunteers dilated the MCA (9% increase in diameter) to the same extent as in the present study [12].

The first is the necessity for a loading dose at the beginning (the first day or two) of a treatment regimen and the considerably lower dose requirement thereafter to sustain suppression.

Compared to the phage-free wild type CN13/87, the lysogenized CN13/87 exhibited significantly increased virulence and caused multi-organ damages in mice at considerably lower infection doses.

In terms of the maximum surface dose rate, all concrete containers showed considerably lower surface dose rate than the existing carbon steel container.