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Their main adverse effects are heart damage (cardiotoxicity), which considerably limits their usefulness, and vomiting.
The existing delivery infrastructure often considerably limits the extent of potential competition in the market.
The isomerization of ABA to the biologically inactive 2E-isomer by light considerably limits its applications in agricultural fields.
A significant challenge for ESAs with a wavenumber-length product much <1 is a high radiation Q, QA, which considerably limits the radiation efficiency5,6.
Assembling an entire building out of modules also considerably limits the flexibility of architects to create distinctive shapes that can symbolize a city "Feasible?
In a statement, Siemens said that its "role as a minority shareholder considerably limits the entrepreneurial maneuverability" of the company and that it no longer made sense to continue working with Areva.
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Most of the phase III trials on AEDs in children have major methodological limitations that considerably limit meaningful conclusions about comparative efficacy between old and new molecules.
However, these interventions tend to be led by highly trained health professionals; considerably limiting their long-term sustainability, due to high cost and limited availability of qualified professionals, especially in non-metropolitan areas.
We have attempted to circumvent this limitation by restricting the analysis to HPV-positive-LSIL, but this considerably limited the power of our study.
Mineral resources are considerably limited.
The privilege of an ordinary witness is considerably limited.
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CEO of Professional Science Editing for Scientists @ prosciediting.com