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Interestingly, U87 cells transduced with anti-miR-125b were considerably less resistant to TMZ than anti-miR-125b transduced LN-18 cells, which might be because of the fact that anti-miR-125b induces cell cycle arrest in G1/G0 in the former.
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Similarly, treatment with Danusertib caused resistance in a dose-dependent manner however, resistant clones occurred considerably less frequently than with IM treatment.
However, resistant clones occurred considerably less frequently compared to IM.
After acid treatment, the morphological analysis of bagasse samples shows that the amount of pith was reduced considerably, which indicates that pith is less resistant to acid degradation than the fiber structures that prevail.
Notably, although some disease symptoms were seen in the resistant cultivar (R), it was considerably less than the damage seen in the susceptible (S) cultivar.
These field populations were highly resistant to pyrethroids, demonstrated by an observed mortality rate that was considerably less than the WHO 90% threshold for resistance.
Interestingly, the emergence of resistant clones during Danusertib exposure in vitro occurred considerably less frequently than with comparable concentrations of IM.
Because it appeared that we had selected for cells that were intrinsically more resistant to curcumin, we predicted that the surviving lines would be considerably less sensitive to curcumin than the original lines.
Because metronidazole is considerably less expensive than oral vancomycin and possibly less likely to promote the selection of vancomycin-resistant Enterococcus spp., practice guidelines have recommended metronidazole as first-line treatment for CDAD [ 50, 51].
Pennsylvania is considerably less elastic.
Almost all make considerably less.
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